Gene: NRAS ×
Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913254
rs121913254
NRAS
A 0.780 GeneticVariation CLINVAR We generated mutant BRAF(V600E) melanoma cells that exhibit resistance to PLX4720, the tool compound for vemurafenib, that co-expressed mutant (Q61K) NRAS. 23076151

2012
dbSNP: rs121913255
rs121913255
NRAS
A 0.700 CausalMutation CLINVAR SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor. 23076151

2012
dbSNP: rs121913255
rs121913255
NRAS
G 0.700 CausalMutation CLINVAR SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor. 23076151

2012
dbSNP: rs1057519695
rs1057519695
NRAS
CC 0.800 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs1057519695
rs1057519695
NRAS
CA 0.800 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs11554290
rs11554290
NRAS
G 0.800 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs11554290
rs11554290
NRAS
C 0.800 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs11554290
rs11554290
NRAS
A 0.800 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913254
rs121913254
NRAS
C 0.780 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913237
rs121913237
NRAS
T 0.740 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913237
rs121913237
NRAS
A 0.740 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913237
rs121913237
NRAS
G 0.740 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913250
rs121913250
NRAS
G 0.720 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913250
rs121913250
NRAS
A 0.720 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913250
rs121913250
NRAS
T 0.720 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121434595
rs121434595
NRAS
G 0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121434595
rs121434595
NRAS
A 0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121434596
rs121434596
NRAS
G 0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121434596
rs121434596
NRAS
T 0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121434596
rs121434596
NRAS
A 0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913255
rs121913255
NRAS
A 0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs121913255
rs121913255
NRAS
G 0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
dbSNP: rs1057519695
rs1057519695
NRAS
CA 0.800 CausalMutation CLINVAR RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. 20179705

2010
dbSNP: rs1057519695
rs1057519695
NRAS
CC 0.800 CausalMutation CLINVAR RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. 20179705

2010
dbSNP: rs11554290
rs11554290
NRAS
C 0.800 CausalMutation CLINVAR RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. 20179705

2010